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Figure 4-2
A close correlation exists between the minimum alveolar
concentration (MAC) of various anesthetics, preventing a response to surgical incision
in humans, and the inspired dose of an anesthetic (ED50
) required to abolish
the righting reflex in the mouse. (Data from references [5]
[8]
[180]
and from
Eger EI II, Rutherford, NJ: Desflurane: A Compendium and Reference. Healthpress
Publishing Group, 1993, p 13.)
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