Figure 21-6
Changes in cerebral blood flow (CBF) and the cerebral
metabolic rate of oxygen (CMRO2
) caused by intravenous anesthetic agents.
The data are derived from human investigations and are presented as the percent
change from unanesthetized control values. Dexmedetomidine CMR values were determined
on a background of 0.5% isoflurane anesthesia. See the text for details. No data
for the CMRO2
effects of midazolam in humans are available. (Data
from references [149]
[150]
[151]
[152]
[153]
[154]
[155]
[156]
[157]
[158]
[159]
[160]
.)
