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Patient Characteristics

Most patients seen in ambulatory surgical facilities are classified as ASA physical status I or II. However, because of improved anesthesia and surgical care, increasing numbers of medically stable ASA physical status III (and even some IV) patients are able to undergo operations away from conventional medical centers.[2] In a large, prospective outcome study by Warner and coworkers,[10] 24% of ambulatory surgical patients were ASA physical status III, and these patients had a low incidence of morbidity, similar to ASA I and II patients ( Table 68-3 ). Other studies have also shown that patients with preexisting medical conditions do not have an increased incidence of perioperative complications or unexpected admissions.[47] This comparable incidence of complications was attributed to prudent patient selection, careful preoperative evaluation, and close communication among surgeons, anesthesiologists, and primary care physicians.

The risk of complications can be reduced if preexisting medical conditions are under good control for at least 3 months before the operation. Therefore, the ASA physical status should not be considered in isolation because the type of surgical procedure, the anesthetic technique, and a multitude of social factors can also influence decisions regarding patient suitability. [48] Even morbid obesity (body mass index >35 kg/m2 ) is no longer considered an exclusionary criterion for day-case surgery[49] ; morbidly obese outpatients can be successfully managed with a facemask for brief procedures.[50] However, patients with
TABLE 68-3 -- Relationship between American Society of Anesthesiologists physical status and postoperative morbidity and mortality
ASA Physical Status Patients (n, %) Major Morbidity (n)
I (healthy patient) 14,609 (32) 6
II (mild systemic disease) 19,614 (43) 17 *
III (severe systemic disease with functional limitation) 10,867 (24) 8
IV (severe systemic disease, constant threat to life) 0


V (moribund, unlikely to survive 24 hr) 0
From Warner MA, Shields SE, Chute CG: Major morbidity and mortality within 1 month of ambulatory surgery and anesthesia. JAMA 270:1437, 1993. Copyright 1993. American Medical Association.
*A total of four deaths were reported within 30 days of the surgical procedure (two were related to motor vehicle accidents).






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preexisting cardiovascular (e.g., hypertension, congestive heart failure, angina) and respiratory (e.g., asthma, chronic obstructive pulmonary disease) conditions, as well as morbid obesity, had a higher incidence of perioperative morbidity than did healthy outpatients undergoing similar procedures on an ambulatory basis.[30] As expected, smoking was associated with an increased risk of respiratory complications and postoperative would infection in patients undergoing ambulatory surgery.[51] Interestingly, the presence of obstructive sleep apnea syndrome was not associated with an increased risk of unanticipated admission to the hospital.[18]

Susceptibility to Malignant Hyperthermia

MH-susceptible patients can be successfully managed with nontriggering anesthetics (e.g., local anesthesia) in the outpatient setting (see Chapter 29 ). The decision to admit a patient postoperatively should be based on clinical criteria because admission solely on the basis of MH susceptibility is no longer considered appropriate.[52] If anesthesia and surgery have been uneventful, MH-susceptible patients should be observed for at least 4 hours postoperatively and may then be safely discharged home.[53] Patients and their families should be advised about the signs and symptoms of MH, in addition to the usual postoperative instructions.

Extremes of Age

Although the acceptability of patients at the extremes of age (i.e., <6 months and >70 years) has been questioned, age alone should not be considered a deterrent in the selection of patients for ambulatory surgery (see Chapter 60 and Chapter 62 ). Many studies have failed to demonstrate an age-related increase in recovery time or incidence of complications after outpatient anesthesia.[54] Even the socalled elderly elderly patient (>100 years) should not be denied ambulatory surgery solely on the basis of age.[55] In fact, elderly patients experience less postoperative pain, dizziness, and emetic symptoms than their younger counterparts.[56] Nevertheless, elderly outpatients may experience a higher incidence of perioperative cardiovascular events, and recovery of fine motor skills and cognitive function is slowed with increasing age. Therefore, elderly outpatients may require a greater degree of supervision after discharge than their younger counterparts. Social factors, including lack of transportation, a responsible escort, or a caretaker at home, may make it difficult for some elderly patients to undergo ambulatory procedures.

On the other extreme, ex-premature infants (gestational age <37 weeks) recovering from minor surgical procedures under general anesthesia have an increased risk for postoperative apnea.[57] Controversy exists regarding the postconceptual age after which no further risk remains.[58] Most studies suggest that the risk is greatest in premature infants younger than 46 weeks' postconceptual age.[59] [60] However, some authors have reported that the risk of apnea may persist until the 60th postconceptual week.[61] Anemia (hematocrit <30%) independently increases the risk of postoperative apnea in former preterm infants less than 60 weeks' postconceptual age.[62] Treatment with high-dose caffeine may prevent prolonged apnea and desaturation in this patient population, but careful postoperative monitoring is still recommended. [63] A combined analysis has determined the following: (1) apnea was strongly and inversely related to both gestational and postconceptual age; (2) an associated risk factor was continuing apnea at home; (3) infants who were small for gestational age seemed to be somewhat protected from apnea; (4) anemia was a significant independent risk factor, particularly for infants less than 43 weeks' postconceptual age; and (5) no relationship exists between apnea and a history of necrotizing enterocolitis, respiratory distress syndrome, bronchopulmonary dysplasia, or intraoperative use of opioid analgesics and muscle relaxants.[64]

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