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VENTILATORY AND RESPIRATORY CHANGES DURING LAPAROSCOPY

Intraperitoneal insufflation of carbon dioxide (CO2 ), the currently routine technique to create pneumoperitoneum for laparoscopy, results in ventilatory and respiratory changes and can cause four principal respiratory complications: CO2 subcutaneous emphysema, pneumothorax, endobronchial intubation, and gas embolism.[4]

Ventilatory Changes

Pneumoperitoneum decreases thoracopulmonary compliance. Compliance is reduced by 30% to 50% in healthy,[5] [6] [7] [8] [9] [10] obese,[11] [12] [13] and American Society of Anesthesiologists (ASA) class III or IV patients, but the shape of the pressure-volume loop does not change ( Fig. 57-1 ). After the pneumoperitoneum is created and kept constant, compliance is not affected by subsequent patient tilting[14] or by increasing


Figure 57-1 Change in total respiratory compliance during pneumoperitoneum for laparoscopic cholecystectomy. The intra-abdominal pressure was 14 mm Hg, and the head-up tilt was 10 degrees. The airway pressure (Paw) versus volume (V) curves and data were obtained from the screen of a Datex Ultima monitoring device. Curves are generated for before insufflation (A) and 30 minutes after insufflation (B). Values are given for tidal volume (TV, in mL); peak airway pressure (Ppeak, in cm H2 O); plateau airway pressure (Pplat, in cm H2 O); total respiratory compliance (C, in mL/cm H2 O); and end-tidal carbon dioxide tension (PETCO2 , in mm Hg).

the minute ventilation required to avoid intraoperative hypercapnia. Reduction in functional residual capacity due to elevation of the diaphragm[15] and changes in the distribution of pulmonary ventilation and perfusion from increased airway pressure can be expected. However, increasing IAP to 14 mm Hg with the patient in a 10- to 20-degree head-up or head-down position does not significantly modify physiologic dead space or shunt in patients without cardiovascular problems.[16] [17] [18]

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