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Chapter 39 - Neuromuscular Monitoring


Jørgen Viby-Mogensen


Traditionally, the degree of neuromuscular block during and after anesthesia is evaluated with clinical criteria alone. However, many studies have documented that routine clinical evaluation of recovery of neuromuscular function does not exclude clinically significant residual curarization.[1] [2] [3] [4] Therefore, there is a growing understanding that more attention should be paid to objective monitoring of the degree of neuromuscular block during and after anesthesia and to the problems of residual curarization.[5] [6]

In awake patients, muscle power can be evaluated through tests of voluntary muscle strength, but during anesthesia and recovery from anesthesia this is not possible. Instead, the clinician uses clinical tests to assess muscle power directly and to estimate neuromuscular function indirectly (muscle tone, the feel of the anesthesia bag as an indirect measure of pulmonary compliance, tidal volume, and inspiratory force). All of these tests, however, are influenced by factors other than the degree of neuromuscular blockade. Therefore, whenever more precise information regarding the status of neuromuscular functioning is desired, the response of muscle to nerve stimulation should be assessed. This procedure also takes into account the considerable variation in individual response to muscle relaxants.

This chapter reviews the basic principles of peripheral nerve stimulation and the requirements for effective use of nerve stimulators. It also describes the response to nerve stimulation during depolarizing (phase I and phase II) and nondepolarizing neuromuscular blocks. Finally, this chapter discusses methods of evaluating evoked neuromuscular responses both with and without the availability of recording equipment.

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