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Hyperventilation activates excitable seizure foci, and in rare cases, it may produce electroencephalographic evidence of cerebral ischemia even in awake subjects.[54] Hypoventilation, unless severe and associated with hypoxemia, has only indirect effects resulting from increased CBF. In the anesthetized patient, hypoventilation-associated increases in CBF may have effects similar to those seen with increasing end-tidal tension of volatile anesthetics.[55]
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