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Untoward Events

One of the suggested reasons for monitoring the brain of the anesthetized patient is to enable detection of injuries to the nervous system that would not be otherwise apparent. Although there are hundreds of such case reports in the literature and many in our experience, the cost-effectiveness of such monitoring is not clear. In a case being prepared for publication, severe electroencephalographic changes occurred at the beginning of a carotid endarterectomy, before surgical incision, and were not associated with any other vital sign changes or hypotension. Immediate angiography revealed acute carotid occlusion and completely changed the operation performed, and the patient recovered completely. Some intraoperative events may lead to a CNS insult that, if detected early, can be rapidly reversed or treated to prevent permanent injury. However, given the rarity of such


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TABLE 38-5 -- Criteria for determination of brain death
Absent cerebral and brainstem functions
Well-defined, irreversible cause
Persistent absence of all brain function after observation or treatment
Hypothermia, drug intoxication, metabolic encephalopathy, and shock excluded
Adapted from Darby JM, Stein K, Grenvik A, et al: Approach to management of the heart beating "brain dead" organ donor. JAMA 261:2222, 1989.

events, it is extremely unlikely that such monitoring could be shown to be beneficial in any foreseeable randomized trial. If the at-risk patient can be identified preoperatively, electroencephalographic monitoring may be useful in detecting untoward CNS events during anesthesia, such as a new stroke after elective general surgery.

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