Figure 47-7 Algorithm of the evaluation and initial therapy of a patient with suspected perioperative coagulopathy. The evaluation is based on the clinical scenario and is affected by the type and location of injury, the amount of fluid administered, and the age and body temperature of the patient. DDAVP, 1-deamino-8-D-arginine vasopressin, a vasopressin analog also known as desmopressin acetate; PT, prothrombin time; PTT, partial thromboplastin time. (Adapted from Habibi S, Corrsin DB, McDermott JC, et al: Trauma and massive hemorrhage. In Muravchick S, Miller RD (eds): Atlas of Anesthesia: Subspecialty Care. New York, Churchill Livingstone, 1998, pp 6.2–6.17.)