Figure 40-3 Major autonomic thermoregulatory response thresholds in volunteers given desflurane, alfentanil, dexmedetomidine, or propofol. All the anesthetics slightly increase the sweating threshold (triggering core temperature) while markedly and synchronously decreasing the vasoconstriction and shivering thresholds. Standard deviation bars smaller than the data markers have been deleted. (Data from references ^{[21] [22] [23] [24]} )