Figure 12-30 Performance errors over time for fentanyl by use of the pharmacokinetics reported by McClain and Hug (A) and Scott and Stanski (B) and a parameter set derived from these observations (C). (From Shafer SL, Varvel SL, Aziz N, et al: The pharmacokinetics of fentanyl administered by computer controlled infusion pump. Anesthesiology 73:1091–1102, 1990.)


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