Figure 8-11 ELISA screening of halothane hepatitis patients' sera for antibodies that react with trifluoroacetylated 58-kilodalton and native 58-kilodalton proteins. All sera from 40 halothane hepatitis patients and 32 control patients were assayed at a 1:100 dilution. (Adapted from Martin JL, Reed GF, Pohl LR: Association of anti-58 kDa endoplasmic reticulum antibodies with halothane hepatitis. Biochem Pharmacol 46:1247–1250, 1993.)