Figure 8-9 Immunochemical detection of trifluoroacetylated proteins in the livers of mice 24 hours after treatment with (R)- or (S)-halothane. A, Mouse treated with (R)-halothane (original magnification ×50). B, Mouse treated with (S)-halothane (original magnification ×50). (From Njoku D, Laster MJ, Gong DH, et al: Biotransformation of halothane, enflurane, isoflurane and desflurane to trifluoroacetylated liver proteins: Association between protein acylation and liver injury. Anesth Analg 84:173–178, 1997.)