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Figure 8-3
Pharmacogenetics of nortriptyline. Mean plasma concentrations
of nortriptyline after a single 25-mg oral dose are shown in subjects with 0, 1,
2, 3, or 13 functional CYP2D6 genes. (Adapted
from Weinshilboum R: Inheritance and drug response. N Engl J Med 348:529–537,
2003.)
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