|
Figure 8-1
Effects of drug metabolism on excretion. Lipophilic
(fat-soluble) drugs are metabolized to form relatively more hydrophilic (water-soluble)
metabolites than the parent drug, and these metabolites are more easily excreted.
(From Weinshilboum R: Inheritance and drug response. N Engl J Med 348:529–537,
2003.)
|
|