Figure 1-14 A, Richard Gill returned from Ecuador in 1938 with 11 kg of a dark tarlike paste from which Squibb and Sons, Inc., prepared the sterile, injectable solution, Intocostrin. B, Harold Griffith and Enid Johnson (not shown) used Intocostrin in 43 cases of abdominal surgery with success in 1942. (Courtesy of the Guedel Memorial Anesthesia Center, San Francisco, CA.)