Figure 77-11 Cardiovascular and metabolic responses after trauma and sepsis in 10 septic and 16 nonseptic patients. Mean values over the postinjury course for cardiac index (CI) and oxygen consumption (ψO₂ ) are shown for trauma patients who developed sepsis (ST) and compared with those who had nonseptic courses. Notice the increase in CI and ψO₂ in ST patients as sepsis becomes established between 5 and 7 days after injury. (Adapted from Sganga G, Siegel JH, Brown C, et al: Reprioritization of hepatic plasma protein release in trauma and sepsis. Arch Surg 120:187, 1985.)