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Figure 7-1
End-systolic pressure-volume (top)
and stroke work versus end-diastolic volume relationships (bottom)
before (control 1 [C1
]); during 0.6, 0.9, and 1.2 minimum alveolar concentrations
(MACs); and after isoflurane (control 2 [C2
]) in an experiment in an open-chest
dog. (Adapted from Hettrick DA, Pagel PS, Warltier DC: Desflurane, sevoflurane,
and isoflurane impair canine left ventricular-arterial coupling and mechanical efficiency.
Anesthesiology 85:403–413, 1996.)
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