Figure 51-8 Sequential sufentanil clearance during the first month of life in three neonates with congenital heart disease. Clearance of sufentanil increases above adult rates within the neonatal period. (Data from Greeley WJ, de Bruijn NP: Changes in sufentanil pharmacokinetics within the neonatal period. Anesth Analg 67:86, 1988.)


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