Figure 5-23 At time zero, the inspired gas was changed from 21% oxygen/79% nitrous oxide to 21% oxygen/79% nitrogen. Arterial oxygen subsequently fell in association with the outpouring of nitrous oxide. (Adapted from Sheffer L, Steffenson JL, Birch AA: Nitrous oxide-induced diffusion hypoxia in patients breathing spontaneously. Anesthesiology 37:436–439, 1972.)


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