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John Snow

Although William T. G. Morton directed his energy to anesthesia after 1846, he also pursued patent claims and remuneration more often than administration of anesthesia.[482] Most historians therefore suggest that John Snow ( Fig. 1-21 ) was the first full-time anesthesiologist. He promoted anesthesiology as a subject of scientific inquiry and through his own example established it as a worthy profession.

John Snow was born in York, England on June 15, 1813, the oldest child in a farming family. His early years


Figure 1-21 John Snow is considered by many to be the first full-time anesthesiologist. His scientific and professional career became a model for future practitioners. (Courtesy of the National Library of Medicine, Bethesda, MD.)

were spent in attendance at a private school in York and working on the family farm. At the age of 14, he became an apprentice to William Hardcastle, a surgeon in Newcastle. Four years later, a cholera epidemic erupted in Newcastle, and while attending those afflicted with this disease, Snow made several observations that proved to be valuable in later years. At 23 years of age, he began the formal study of medicine at the Hunterian School of Medicine in London. This was a short course, and only 1 year later, he passed his examinations and was entered as a member of the Royal College of Surgeons of England.

Benjamin Ward Richardson, who was intimate with Dr. Snow and who wrote a short biography, characterized him as an individual who sought "only the truth, the naked truth for its own sake without consideration of honor or profit." Snow's initial attempts to establish a private general practice were thwarted by his inability to attract paying patients. He would not engage in the common practice of writing prescriptions for neurotic patients. Consequently, his time was spent volunteering at the Charing Cross Hospital and in scientific pursuits and reading. In 1841, at the age of 30, he read his first paper, "Asphyxia and on the Resuscitation of Newborn Children," before the Medical Society of London. This first paper describes positive-pressure ventilation for resuscitation of the depressed newborn and indicates his penchant for matters relating to anesthesia. This interest took firm control of his life after the news from America arrived in London that operations could be performed without pain after the inhalation of sulfuric ether.

Snow took up the exclusive practice of ether administration and within 1 year had written the first of his two landmark books on inhalation anesthesia. When Dr. James Simpson introduced chloroform in October 1847, Snow enthusiastically embraced the new agent. His chloroform inhaler was superior to prior devices in that it used valves to prevent rebreathing. He classified the stages of anesthesia and studied the effect of ether[355] and chloroform on animals and humans to learn the concentrations required for anesthesia at various stages. The precision and detail with which this work was performed was not to be accomplished again for nearly 100 years, when the vapor pressures of inhalation anesthetics necessary for anesthesia were determined. His contemporaries recognized his clinical skills to be of the highest caliber, and he was recommended to provide anesthesia for the delivery of two of Queen Victoria's children. Snow delivered chloroform in 1853 for the birth of Prince Leopold and in 1857 for the birth of Princess Beatrice.

In 1854, a rampant cholera epidemic broke out in the Charing Cross district, and Snow used his prior experience with the disease to analyze the causative factors involved in transmission. His advice to remove the handle of the Broadstreet water pump because of suspected transmission through the water supply was carried out, and the epidemic subsided. His theories on transmission of cholera were published at his own expense in the London Medical Gazette. His last treatise, On Chloroform and Other Anesthetics, [446] was in its final stages of completion when he died of kidney disease complicated by a stroke on June 14, 1858, at the age of 45.

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