Nonionizing Radiation: Lasers
Laser is an acronym for light amplification
by stimulated emission of radiation. Lasers produce infrared, visible,
or ultraviolet light. Although the radiation from lasers is nonionizing, it is potentially
unsafe both because of its intensity and because of the matter release from tissues
during treatment.
Lasers are used in many surgical specialties, including ophthalmology,
plastic surgery, gynecology, neurosurgery, urology, head and neck surgery, and gastrointestinal
surgery. A surgical laser produces intense focused electromagnetic radiation to
cut or destroy tissues. The radiation is usually infrared or visible light and is
created in a "laser medium" that is stimulated by high-intensity energy to release
photons of identical wavelength (coherent or monochromatic light) from a laser chamber.
The material in the medium (e.g., carbon dioxide, argon) is responsible for the
wavelength produced by the laser. Of those in common clinical use, carbon dioxide
and neodymium:yttrium-aluminum-garnet (Nd:YAG) lasers emit light in the far-infrared
and near-infrared wavelengths, respectively; argon and tunable dye lasers produce
visible light.[22]
The choice of laser used is
based on the surgical goal.
Eye injuries are the greatest risk to personnel working near lasers.
Strict standards for protection have been developed on the basis of current understanding
but are subject to periodic revision as more experience is gained with these instruments.
Either direct exposure or reflected radiation may cause eye damage. Injuries include
burns to the cornea and retina, destruction of the macula or optic nerve, and cataract
formation. Protective eyewear is designed to filter out the radiation produced by
a specific type of laser while still permitting vision. For example, clear plastic
lenses block the far-infrared (10.6-µm) radiation from carbon dioxide lasers
but provide no protection against the near-infrared (1060-nm) radiation emitted by
Nd:YAG lasers. The type of protection provided by a given filter is marked on the
frame of the goggles and should be checked before use. Filters that are scratched
or crazed should not be used. Because certain filters block portions of the visible
spectrum, it is prudent to confirm preoperatively that patient monitors can be seen
and interpreted correctly with goggles in place. Protective eyewear is recommended
for all personnel because reflected radiation can be as hazardous as direct radiation
and the intensity is not diminished significantly in the distances traveled in the
average operating room.[22]
Although the plume—the vapor and cellular debris produced
during laser surgery—is commonly malodorous, until recently it was not considered
to be other than unpleasant. Now, there is concern that the plume may present a
significant risk. The median size of particles in plume samples obtained intraoperatively
is 0.31 µm in diameter and ranges from 0.1 to 0.8 µm. Most surgical
masks do not trap such small particles.[23]
Even
after filtration of particles greater than 0.5 µm in diameter, exhaust smoke
from tissues treated with a carbon dioxide laser causes pulmonary lesions in laboratory
animals. If all particles larger than 0.1 µm are scavenged, no lung damage
occurs, thus pointing out the importance of scrupulous removal of the plume.[24]
Under experimental conditions, viable bacteria have been recovered from the plume
emanating from laser irradiation.[25]
Intact DNA
from human papillomavirus (HPV) has been detected in the vapor from both laser-treated
plantar warts and genital condylomata.[26]
[27]
More frightening is that human immunodeficiency virus (HIV) proviral DNA has been
found in laser smoke produced by vaporizing cultures of HIV-positive cells.
Although these experiments, which used tissue cultures, do not
replicate the clinical situation, they stress the
importance of strict attention to smoke removal.[28]
With adequate evacuation and filtration using equipment specifically designed to
scavenge such vapors, it is unlikely that operating room personnel will be contaminated
by laser-dispersed HPV DNA.[27]
However, a case
report has documented the appearance of laryngeal papillomas in a laser surgeon who
had previously treated several patients infected with anal condylomata without the
benefit of a laser smoke evacuator. Tissue from the surgeon's laryngeal tumors contained
HPV DNA types 6 and 11, the same viral types that are commonly harbored by anogenital
condylomata. Though not conclusive, these findings suggest that the laryngeal papillomas
may have been caused by inhaled virus particles.[29]
It therefore seems prudent to ensure that the utmost care is taken to scavenge all
vaporized debris.