Intravenous Anesthesia

Intravenous anesthetics behave similarly and are unlikely to be affected within the usual clinical range of ambient pressure. There is no evident alteration in the pharmacokinetics of either meperidine^[86] or pentobarbital^[87] at ambient pressures up to 6 ATA. For therapeutic lung lavage, we have provided general anesthesia at ambient pressures up to 3 ATA with the use of conventional doses of ketamine and benzodiazepines or propofol and narcotics with non-depolarizing muscle relaxants.