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Optimal Anesthetic Techniques

The optimal anesthetic technique in the ambulatory setting would provide for excellent operating conditions, rapid "fast-track" recovery without postoperative side effects or complications, and a high degree of patient satisfaction. In addition to increasing the quality and decreasing the cost of anesthetic services, the ideal anesthetic technique would also improve operating room efficiency (e.g., turnover times) and provide for an earlier discharge home. Local anesthesia with intravenous sedation (i.e., MAC techniques), regional (peripheral) blocks, spinal anesthesia, and general anesthesia are all commonly used for ambulatory surgery. However, opinions differ regarding the "best" anesthetic technique, even for superficial surgical procedures. [369] [478] [479] [480] [481] [482] [483] [484] [485] [486] [487] [488] [489] Rather than simply generalizing about the best anesthetic technique for ambulatory surgery, it would be better to individually analyze each surgical procedure.[490]

In the current cost-conscious environment, it is important to also examine the impact of anesthetic techniques on the perioperative process because prolonged recovery times and reduced efficiency and productivity contribute to the increased cost of surgical care.[431] [432] In addition, patient satisfaction with the perioperative experience and quality of recovery is improved when the anesthetic technique chosen for the procedure is associated with a low incidence of postoperative side effects. For example, the routine use of prophylactic antiemetic drugs during general anesthesia has been found to increase patient satisfaction in "at-risk" outpatient surgical populations.[152] Furthermore, the use of local anesthetic infiltration or peripheral nerve blocks, or both, decreases postoperative pain after ambulatory surgery procedures irrespective of the anesthetic technique.[491] [492] [493]

The time required to achieve a state of home readiness (i.e., "fitness" for discharge home) is influenced by a wide variety of surgical and anesthetic factors.[494] [495] However, the major contributors to a delay in discharge after ambulatory surgery are nausea, vomiting, dizziness, pain, and prolonged sympathetic or motor blockade (or both). Although the incidence of PONV can be decreased by the use of prophylactic antiemetic drugs,[491] it remains a common side effect after general anesthesia and prolongs discharge after ambulatory surgery. [150] The primary factor delaying discharge after spinal anesthesia is recovery from the residual motor and sympathetic blockade, which contributes to delayed ambulation and an inability to void. These side effects can be minimized by use of the so-called minidose lidocaine-fentanyl spinal anesthetic technique.[487] [489] Other concerns with spinal anesthesia include back pain, post-dural puncture headache, and transient radicular irritation.[496] [497] Although MAC is associated with the lowest incidence of postoperative side effects, [431] [432] the possibility of transient nerve palsy is a concern when peripheral nerve block techniques are used.[498] [499] [500] Another issue relates to the fact that many patients simply prefer to "be asleep during the operation."

Use of the modern anesthetics (e.g., propofol, sevoflurane, desflurane) in combination with antiemetic prophylaxis with nonopioid analgesic techniques can achieve recovery times that compare favorably with MAC techniques ( Table 68-11 ).[318] [501] [502] These studies demonstrated that outpatients undergoing hernia repair and breast surgery were able to ambulate within 30 minutes and were discharged within 60 minutes. Avoidance of tracheal intubation by using an LMA or a facemask also facilitates a fast-track recovery. When tracheal intubation is required (e.g., laparoscopic procedures, risk factors for aspiration [e.g., diabetics, morbidly obese, esophageal dysfunction]), the use of minimally effective doses of a short-acting opioid analgesic (e.g., remifentanil) or sympatholytic (e.g., esmolol) drug, or both, can facilitate the early recovery process and allow patients to achieve earlier discharge times after ambulatory surgery.[119] [332] [503] [504]

The cost savings associated with use of the newer anesthetic techniques are lost if institutional practices mandate minimum lengths of stay in the phase 1 unit (PACU) and do not permit fast-tracking of patients who emerge rapidly from anesthesia directly to the phase 2 (day-surgery ["step-down"]) unit. Claims of reduced total costs with earlier discharge are commonly based on


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TABLE 68-11 -- Comparison of propofol and desflurane when used in combination with nitrous oxide for maintenance of anesthesia for fast-track, office-based ambulatory surgery

Propofol Desflurane
Age (yr) 57 ± 18 53 ± 17
Weight (kg) 66 ± 14 70 ± 14
Anesthetic time (min) 36 ± 14 40 ± 20
Surgical time (min) 34 ± 14 37 ± 19
Propofol dosage (mg) 319 ± 98 146 ± 137
End-tidal desflurane (%) N/A 2.3 ± 0.6
During the operative period [n (%)]

  Purposeful movement 14 (40) 2 (5) *
  Coughing 3 (9) 4 (10)
In the recovery area [n (%)]

  Nausea 1 (3) 3 (8)
  Vomiting 0 (0) 1 (3)
  Rescue antiemetic 0 (0) 2 (5)
Recovery times (min)

  Awakening 6 ± 2 4 ± 2 *
  Ambulating alone 23 ± 15 14 ± 5 *
  Discharge home 51 ± 14 46 ± 10
After discharge home [n (%)]

  Nausea 1 (3) 4 (10)
  Vomiting 0 (0) 1 (3)
Rescue antiemetic 0 (0) 0 (0)
Values are means ± SD, numbers (n), and percentages (%).
From Tang J, White PF, Wender RH, et al: Fast-track office-based anesthesia: A comparison of propofol vs desflurane with antiemetic prophylaxis in spontaneously breathing patients. Anesth Analg 92:95, 2001.
*P < .05 versus the propofol group.




the assumption that there is a linear relationship between the cost of a clinical service and the time spent providing it. Because personnel costs are semifixed rather than variable, an additional 15- to 30-minute stay in the PACU may not be associated with increased cost to the institution unless the facility is working at or near its capacity.[
505] In that situation, a longer stay is potentially associated with a "bottleneck" in the flow of patients through the operating room suites and recovery areas and thus requires overtime payment to the nurses or the hiring of additional perioperative personnel, or both.

The relationship between decreasing costs and bypassing the PACU ("fast-tracking") appears to be much closer because the major factor in recovery care cost relates to the peak number of patients admitted to the PACU at any given time.[505] Fast-tracking can lead to the use of fewer nurses and a mix of less highly trained, lower-wage nursing aides and fully qualified recovery room nurses and therefore reduces "overtime" personnel costs for busy ambulatory surgery units. Shorter anesthesia times, the ability to bypass the PACU, and a decreased length of stay in the day-surgery unit will reduce total institutional costs.[506] Studies have demonstrated that "fast-tracking" ambulatory surgery patients decreases the time to actual discharge ( Table 68-12 ).[507] [508]


TABLE 68-12 -- Effect of fast-tracking on discharge time and patient satisfaction after outpatient laparoscopy surgery

Conventional Recovery Pathway Fast-Track Recovery Pathway
Age (yr) 30 ± 6 28 ± 5
Weight (kg) 69 ± 22 74 ± 14
Surgery time (min) 36 ± 11 37 ± 12
Home ready (min) 151 ± 50 112 ± 46 *
Discharged home (min) 206 ± 46 159 ± 63 *
Patient satisfaction (%) 93 ± 5 94 ± 4
From Coloma M, Chiu JW, White PF, Armbruster SC: The use of esmolol as an alternative to remifentanil during desflurane anesthesia for fast-track outpatient gynecologic laparoscopic surgery. Anesth Analg 92:352, 2001.
*P < .05 versus the conventional recovery pathway.




The combination of low cost and high patient satisfaction suggests that the highest-quality (cost/outcome) anesthetic may be achievable with a MAC technique, assuming that the surgical procedure is amenable to this anesthetic approach (e.g., superficial surgical and endoscopic procedures). However, the success of MAC techniques is dependent not only on the anesthesiologist but also on the skills of the surgeon in providing effective infiltration analgesia and gentle handling of tissues during the intraoperative period. Superficial operations can be performed under local anesthesia without any monitoring or intravenous adjuvants (so-called unmonitored local anesthesia) in situations in which the local anesthesia is able to provide complete analgesia and patients do not object to being awake and aware of events in the operating room. [509] In a prospective, randomized comparison of local infiltration with spinal and general anesthesia,[510] surgeons in Sweden suggested that technical difficulties and patient pain were "more intense" during surgery under local anesthesia. This finding is consistent with an earlier report by Fairclough and colleagues.[511] However, the researchers in Sweden concluded that "for many patients, local anesthesia can be recommended as the standard procedure for outpatient knee arthroscopy."[510]

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