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Vascular resuscitation is a neglected aspect of neonatal resuscitation. Those who are premature and asphyxiated near the end of labor are especially likely to be hypovolemic.
If the neonate's condition does not improve rapidly with ventilation and tactile stimulation, an umbilical artery catheter should be inserted to measure blood gases and pH, to measure arterial blood pressure, to expand blood volume, and to administer drugs. Most preterm neonates weighing less than 1250 g at birth and 1% to 3% of term neonates require an umbilical artery catheter during resuscitation. It also may be helpful to insert an umbilical venous line whose tip is in the superior vena cava or the right atrium to determine the adequacy of blood volume replacement.
A stopcock should be attached into one end of a 3.5F or 5.0F umbilical artery catheter, and the catheter and stopcock should be flushed with sterile saline. The stump of the umbilical cord is grasped with a clamp and the cord held straight up in the air. The abdomen and umbilical cord are sterilized with an iodine-containing solution, and the abdomen is sterilely draped. Next, a sterile umbilical tape is tied loosely around the cord, and the cord is cut cleanly with a scalpel, leaving 2 cm of stump. The stump is firmly grasped with the gloved fingers of one hand, and one of the two thick-walled umbilical arteries is dilated with a curved iris forceps. With the stopcock filled with fluid, a 3.5F umbilical artery catheter is inserted into the artery if the neonate weighs less than 1500 g, or a 5F catheter is used if the neonate weighs 1500 g or more. After the catheter is inside the vessel, the stopcock should be partially opened. Some resistance may be encountered when the catheter has been advanced 3 to 5 cm into the vessel, but this resistance can usually be overcome by applying steady downward pressure on the catheter. If the catheter cannot advance, a second catheter can be inserted into the other artery while leaving the first catheter in place. This maneuver often causes one or the other vessel to relax and permits one of the catheters to be advanced into the aorta. When blood appears in the catheter, the stopcock should be closed, and the catheter should be advanced 1 to 2 cm, depending on the size of the neonate. Blood should be withdrawn from the catheter, and all air should be removed from the system. (The accidental injection of small amounts of air [<0.1 mL] may obstruct blood flow to the legs for several hours.) The catheter should be attached to a pressure transducer and the arterial pressure measured.
The stump of the umbilical cord is prepared, grasped, and tied as described previously. The single, large, thin-walled
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