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Postoperative Nausea and Vomiting

Laparoscopy is frequently associated with minor postoperative sequelae (see Chapter 68 ) that can persist more than 48 hours and that can significantly delay discharge of outpatients.[221] In addition to postoperative pain of various types, the most frequent complaints are headache, sore throat (in case of endotracheal intubation), and nausea and vomiting. Postoperative nausea and vomiting (PONV) is one of the main complaints after laparoscopy (40% to 75% of patients),[222] [223] [224] and the most important factor determining the length of stay after ambulatory anesthesia.[225] Whereas intraoperative opioids increase the incidence of PONV,[226] [227] propofol anesthesia can markedly reduce the high incidence of these side effects.[225] The effect of N2 O on the incidence of nausea is still controversial.[228] [229] [230] [231] [232] [233] Drainage of gastric contents also reduces PONV.[234] Intraoperative administration of droperidol and the use of ondansetron appear to be helpful in the prevention and treatment of these side effects.[235] [236] [237] [238] [239] Perioperative oxygen supplement halves the incidence of PONV in one study[240] but was ineffective in another study.[241] Transdermal scopolamine reduces nausea and vomiting after outpatient laparoscopy.[222] Analgesic techniques that allow reductions of opioid consumption can contribute to decreasing these symptoms.[242]

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