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Although it is my opinion that neuromuscular function should be monitored objectively whenever a neuromuscular blocking drug is administered to a patient, tactile or visual evaluation of the evoked response is still the most common form of clinical neuromuscular monitoring. The following is a description of how this is best done.
First, for supramaximal stimulation, careful cleansing of the skin and proper placement and fixation of electrodes are essential. Second, every effort should be taken
Figure 39-18
Predicted probabilities of postoperative pulmonary complications
in different age groups in orthopedic, gynecologic, and major abdominal surgery with
a duration of anesthesia of less than 200 minutes. The solid lines represent patients
having residual neuromuscular block (TOF < 0.70) following the use of pancuronium;
the broken lines represent patients with TOF ≥ 0.70 following the use of pancuronium
as well as all patients following the use of atracurium and vecuronium, independent
of the TOF ratio at the end of anesthesia.[99]
Figure 39-19
Typical recording of the mechanical response (Myograph
2000) to TOF nerve stimulation of the ulnar nerve after injection of 1 mg/kg of succinylcholine
(arrow) in a patient with genetically determined
abnormal plasma cholinesterase activity. The prolonged duration of action and the
pronounced fade in the response indicate a phase II block.
Figure 39-20 shows which modes of nerve stimulation can be used at various periperative times.
The nerve stimulator should be attached to the patient before induction of anesthesia but should not be turned on until after the patient is unconscious. Single-twitch stimulation at 1 Hz may be used initially when seeking supramaximal stimulation. However, after supramaximal stimulation has been ensured and before muscle relaxant is injected, the mode of stimulation should be changed to TOF (or 0.1-Hz twitch stimulation). Then, after the response to this stimulation has been observed (the control response), the neuromuscular blocking agent is injected. Although the trachea is often intubated when the response to TOF stimulation disappears, postponement of this procedure for 30 to 90 seconds, depending upon the muscle relaxant used, usually produces better conditions.
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