Figure 5-12 In dogs, when only the right lung was ventilated, the rise of the very soluble anesthetic methoxyflurane in arterial blood was normal (i.e., did not deviate from control), but the rise for the poorly soluble anesthetic cyclopropane was significantly slowed. (Adapted from Stoelting RK, Longnecker DE: Effect of right-to-left shunt on rate of increase in arterial anesthetic concentration. Anesthesiology 36:352–356, 1972.)