Figure 43-7 Meperidine requirements during the first and second postoperative days in patients receiving intravenous lidocaine (filled bars) and in control patients (open bars). Data are expressed as the mean ± SEM. *, p < .02; **, p < .01 compared with control data. (Adapted from Cassuto J, Wallin G, Högström S, et al: Inhibition of postoperative pain by continuous low-dose intravenous infusion of lidocaine. Anesth Analg 64:971, 1985.)