Figure 19-6 Blood supply of the simple liver acinus. The oxygen tension and the nutrient level of the blood in sinusoids decrease from Zone 1 through Zone 3. Note that the lower left side of the figure also depicts Zones 1, 2, and 3 in a portion of an adjacent acinar unit. BD, bile duct; HA, hepatic artery; PV, portal vein; CV, central vein. (Reprinted with permission from Jones AL: Anatomy of the normal liver. In Zakim D, Boyer T [eds]: Hepatology: A Textbook of Liver Disease, 3rd ed. Philadelphia, WB Saunders, 1996, p 3.)