Figure 18-16 Adrenoceptor signaling cascades. G proteins and effectors (AC, adenylyl cyclase; iCAL , L-type calcium current; PLC-β, phospholipase β) are the primary G protein and effectors in the heart. The intracellular signals are DAG (diacylglycerol), IP3 (inositol triphosphate), PKC (protein kinase C), cAMP (cyclic adenosine monophosphate), PKA (protein kinase A), and MAPK (mitogen-activated protein kinase).


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