Figure 13-30 First twitch height (logit scale) versus dose (log scale) 10 minutes after administration of neostigmine and edrophonium given at either 1% (99% block) or 10% (90% block) recovery of the first twitch. (Redrawn from Donati F, Smith CE, Bevan DR: Dose-response relationships for edrophonium and neostigmine as antagonists of moderate and profound atracurium blockade. Anesth Analg 68:13–19, 1989.)