Figure 7-25 Histograms show the effects of isoflurane (ISO) and xenon on the preload recruitable stroke work slope (M_W , top panel), the peak rate of increase of left ventricular pressure (+dP/dt_max , middle panel), and percent segment shortening (%SS, bottom panel) in normal (red bars) and cardiomyopathic (gray bars) dogs receiving 1.5 minimum alveolar concentration (MAC) of isoflurane in the presence and absence of 30%, 50%, and 65% xenon. *, Significantly (P < .05) different from control; †, significantly (P < .05) different from ISO alone; ‡, significantly (P < .05) different from ISO and 30% xenon; ¶, significantly (P < .05) different from the corresponding value in normal dogs.