Figure 7-17 Occluded compared with normal and occluded compared with stenotic zone myocardial blood flow in dogs with steal-prone coronary artery anatomy in the conscious state (C), during 1.1 and 1.9 minimum alveolar concentrations (MACs) of isoflurane (I) anesthesia, during adenosine (A) infusions (0.54 and 1.08 mg/min), and during maintenance of heart rate and arterial pressure at conscious values during the highest doses (BP). Isoflurane does not cause coronary steal, in contrast to significant (P < .05 [*]) reductions in blood flow to collateral-dependent myocardium produced by adenosine. (Adapted from Hartman JC, Kampine JP, Schmeling WT, Warltier DC: Actions of isoflurane on myocardial perfusion in chronically instrumented dogs with poor, moderate, or well-developed coronary collaterals. J Cardiothorac Anesth 4:715–725, 1990.)