 |
|
|
Figure 7-13
Continuous left ventricular (LV) pressure, rate of increase
of LV pressure (LV dP/dt), aortic pressure, left atrial (LA) pressure, LA short-
and long-axis dimensions, and LA volume wave forms and corresponding LA pressure-volume
diagrams resulting from intravenous administration of phenylephrine (200 µg)
were observed in a typical experiment. The LA maximum elastance (solid
circles) and end-reservoir pressure and volume (solid
squares) for each pressure-volume diagram were used to obtain the slopes
(Ees
and Eer
) and extrapolated volume intercepts of the LA
end-systolic and end-reservoir pressure-volume relationships to quantify myocardial
contractility and dynamic chamber stiffness, respectively. (Adapted from
Gare M, Schwabe DA, Hettrick DA, et al: Desflurane, sevoflurane, and isoflurane
affect left atrial active and passive mechanical properties and impair left atrial-left
ventricular coupling in vivo: Analysis using pressure-volume relations. Anesthesiology
95:689–698, 2001.)
|
|
