Figure 63-11 Escalating therapy for severe traumatic brain injury. The goal of therapy is to maintain cerebral perfusion pressure above 70 mm Hg by support of the circulation and control of intracranial pressure. Progressively more intensive therapies are added until this goal is achieved. Decompressive craniotomy is controversial, and decompressive laparotomy is under study at this time. CSF, cerebrospinal fluid.