Figure 6-10 Composite hypoxic pulmonary vasoconstriction (HPV) responses as a function of left pulmonary flow in the same seven chronically instrumented dogs in the conscious state and during sevoflurane and desflurane anesthesia. Neither type of anesthesia affected the magnitude of HPV compared with the response in the conscious state. (Adapted from Lesitsky MA, Davis S, Murray PA: Preservation of hypoxic pulmonary vasoconstriction during sevoflurane and desflurane anesthesia compared to the conscious state in chronically instrumented dogs. Anesthesiology 89:1501, 1998.)