Figure 6-8 Concentration-dependent inhibition of hypoxic pulmonary vasoconstriction (HPV) in isolated rabbit lungs by desflurane (solid squares) and halothane (open squares). Values are mean ± SEM and expressed as a percentage of control (*P < .05 versus control HPV). The half-maximum inhibiting effect (ED₅₀ ) values were within the range of 1 to 2 minimum alveolar concentrations (MACs) for rabbits for both agents. (Reproduced from Loer SA, Scheeren TWL, Tarnow J: Desflurane inhibits hypoxic pulmonary vasoconstriction in isolated rabbit lungs. Anesthesiology 83:552, 1995.)