Figure 6-7
Effect of halothane on phosphatidylcholine (PC) synthesis
by alveolar type II cells. PC synthesis measured as the incorporation of [3
H-methyl]-choline
into PC and expressed as disintegrations per minute per microgram of intracellular
protein (*P < .05, **P
< .01 versus respective control.) A, Effect of
increasing halothane concentration with 4-hour exposure. B,
Effect of increasing exposure time to 2% halothane. (Adapted from Molliex
S, Crestani B, Dureuil B, et al: Effects of halothane on surfactant biosynthesis
by rat alveolar type II cells in primary culture. Anesthesiology 81:668, 1994.)
