Figure 54-3 Autoregulation of renal blood flow (RBF) and the glomerular filtration rate (GFR). The relationships between RBF, GFR, and urine flow rate (UFR) and mean renal arterial pressure in dogs are shown as renal arterial pressure is varied from 20 to 280 mm Hg. Autoregulation of RBF and GFR is observed between about 80 and 180 mm Hg. (Redrawn from Hemmings HC: Anesthetics, adjuvants and drugs and the kidney. In Malhotra V [ed]: Anesthesia for Renal and Genitourinary Surgery. New York, McGraw-Hill, 1996, p 18.)