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The first anesthetics were given to ameliorate the pain associated with dental extractions and minor surgery. As the complementary fields of surgery and anesthesiology matured together, new skills were required of the anesthesiologist, including expertise in resuscitation, fluid replacement, airway management, oxygen transport, operative stress reduction, and postoperative pain control. Today, personnel from the anesthesiology department are scattered in several locations throughout the hospital, from the ambulatory care center to the intensive care unit. Organizing the background of these various activities into a coherent historical document is therefore complicated by the diverse roles that anesthesiologists play in the modern hospital.
One approach to the history of anesthesiology is to relate in detail the events surrounding the 1846 public demonstration of ether anesthesia by William T. G. Morton (1819–1868).[1] [2] [3] [4] This event represents the starting point from which anesthesiology emerged as a specialty. Although the ether demonstration was dramatic and enacted by interesting personalities, it was just the opening act of the pain control story. Since 1846, there has been enormous progress and change in the specialty of medicine that has become known as anesthesiology, and these changes often have occurred in small, incremental steps that are hardly noteworthy on their own. Most operations in the modern operating room could not have been performed before the great progress in anesthetic practice that took place in the years between 1925 and 1960, but historians often overlook these advances, because they were introduced without the drama and spectacle of previous developments.
In addition to the advancements of the 20th century, it is necessary to look prior to mid-19th century to appreciate the groundwork laid by those curious individuals who sought a scientific understanding of cardiopulmonary physiology and pain. These fundamental discoveries provide the physiologic foundation for safe anesthetic practice. A brief survey of these developments is provided in the opening sections of the following narrative. Dentists, priests, musicians, pediatricians, engineers, ophthalmologists, neurophysiologists, pharmacologists, urologists, otolaryngologists, surgeons, ministers, dilettantes, philosophers, physiologists, missionaries, chemists, South American Indians, and anesthesiologists all had a role in shaping the practice of contemporary anesthesiology, one of the most fascinating stories in the history of medicine.
I have attempted to describe and reference the origins of ideas relating to modern anesthetic practice, but the issue of priority is vague on some topics and may be open to question by other historians of specific subjects. I have attempted to verify information from several sources, including original manuscripts whenever possible. Notably lacking are early references to anesthetic methods in Asia, because these texts and manuscripts are difficult to obtain. The historical developments of the subspecialties are not documented, but that information can be obtained from specialized textbooks. Perhaps Sir William Osler (1849–1919) expressed the difficulties of the medical historian best when he related the History of British Medicine in an address to the British Medical Association in 1897.[5]
To trace successfully the evolution of any one of the learned professions would require the hand of a master—of one who, like Darwin, combined a capacity for patient observation with philosophic vision. In the case of medicine, the difficulties are enormously increased by the extraordinary development, which has taken place during the 19th century. The rate of progress has been too rapid for us to appreciate, and we stand bewildered and as it were, in a state of intellectual giddiness, when we attempt to obtain a broad, comprehensive view of the subject.
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