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Latex Allergy

Since 1992, health care workers who come in contact with infectious materials have been required to use barrier precautions, including protective gloves. [31] Coincidental with this mandate has been a progressively increasing number of allergic reactions to latex-containing products, especially in health care workers. Components used in making gloves, including latex, accelerators (used to shorten the manufacturing process), and glove powder, have been implicated as causes. Responses may be limited to irritant contact dermatitis, a delayed type IV reaction mediated by T cells, or they may be manifested by more serious IgE-mediated type I reactions. The latter include contact urticaria, rhinitis, conjunctivitis, asthma, and occasionally, full-blown anaphylactic shock.[100]

The prevalence appears to be higher in persons who have regular contact with latex-containing products. One report indicated that nearly 16% of the staff of a single anesthesia department had positive skin test results to latex, although of those tested, respiratory changes during work hours developed in far fewer.[101] Allergic responses to latex are also associated with a history of atopy and with allergies to certain foods such as avocado, potato, banana, tomato, chestnuts, kiwi fruit, and papaya. In some individuals, such a severe sensitivity developed that they are no longer able to work in areas containing airborne latex particles or to eat food that has come in contact with latex.


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NIOSH has developed recommendations for the prevention of latex allergies as they currently exist. These recommendations include protection of workers from undue exposure to latex, hand washing after removing gloves, and educational programs for hospital workers.[102] Modifications of manufacturing processes for latex products, more accurate methods to assess allergies to latex, and perhaps the development of substitutes are additional goals of the recommendations. Up-to-date information concerning this dynamic area of interest is available on several Internet web sites.

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