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2957

TRADITIONAL CONCEPT OF DEATH OF AN ORGANISM

All living organisms take in oxygen by respiration, distribute the oxygen to peripheral tissues through circulation, and then excrete metabolites by means of the circulation and through respiration. Respiration and circulation are vital to the living organism. Respiration is the functional expression of the brainstem, and cessation of brainstem functions leads to the cessation of respiration. Because the brainstem maintains its function through its supply of oxygen and nutrients, cessation of circulation ultimately leads to cessation of respiration. The functions of the brain, heart, and lungs are mutually dependent and share the basic role of maintaining life. An organism dies when one of these life-sustaining organ systems ceases to function. The traditional concept of death of an organism emphasized the cessation of respiration or circulation, without consideration of the role of the brain. This occurred because assessment of brain function was not easy to accomplish. When mechanical ventilation was not widely used, cessation of brain functions related directly to cessation of respiration, and assessment of brainstem functions was unnecessary.

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