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2818

BRONCHIAL HYGIENE THERAPY

Hospitalized patients often have diminished respiratory effort and impaired mucociliary clearance of pulmonary secretions. A number of factors can contribute to these impairments, including decreased physical activity, pain, altered mental status, and certain medications. These deficiencies can lead to atelectasis and pulmonary infections which may prolong hospital stay and increase mortality. The goal of bronchial hygiene therapy is to supplement airway mucociliary clearance and optimize pulmonary function. The essential components of bronchial hygiene therapy include (1) humidification of the airways, (2) deep breathing and incentive spirometry, (3) chest physiotherapy, (4) noninvasive positive-pressure techniques, and (5) invasive suctioning of the bronchotracheal tree. While many of these specific techniques have been studied in clinical trials, most of these trials were small and inconclusive. Therefore, although bronchial hygiene therapy is clearly important, the optimal regimen remains controversial. In clinical practice, the choice of bronchial hygiene regimen must be individualized.

Humidification

Humidity refers to the level of moisture or water vapor in air. Absolute humidity can be defined as the mass of water vapor in a specific volume of gas (typically expressed as mg/L). Air is fully saturated at its maximum absolute humidity. The maximum absolute humidity is a function of temperature, as shown in Table 75-5 .

Relative humidity is the content of water vapor expressed as a percentage of the maximum absolute humidity at a given temperature. Alveolar air is normally fully saturated. Thus, at body temperature (37°C) alveolar air has an absolute humidity of 44 mg/L and a relative humidity of 100%, yielding a partial pressure of water of 47 mm Hg. Conversely, standard room air at a temperature of 21°C has a 50% relative humidity, or an absolute humidity of 9 mg/L. Inspired air must therefore be warmed and humidified by the airways. Inadequate humidification of inspired gas can lead to dried secretions, poor mucociliary clearance, atelectasis, and pulmonary infections. The administration of dry oxygen lowers the inspired water content, increasing the risk of these complications. The water content of delivered oxygen can be increased with humidifiers or nebulizers.


TABLE 75-5 -- Maximum absolute humidity (MaxAH) at different temperatures
Temperature (°C) MaxAH (mg/L)
 0 4.9
10 9.4
20 17.3
30 30.4
37 43.9
40 51.1
50 83.2

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