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Stereotactic Radiosurgery

Stereotactic radiosurgery is the delivery of a large radiation dose to ablate tissue localized stereotactically.[202] Sources of ionizing radiation include photon beams produced by either 60 Co gamma ray or linear accelerators and heavy-ion particle beams. The radiation is emitted as multiple beams that can be focused on the desired site. The radiation dose from each beam is small to limit exposure of normal tissue to radiation. However, the radiation dose at the focus of the beams is high to achieve tissue destruction in the desired area.[203] This technique has been used to treat AVMs, dural arteriovenous fistulas, pituitary adenomas, acoustic neuromas, trigeminal neuralgia, and malignant tumors.[204] [205] [206] [207] [208]

The procedure consists of the initial placement of a stereotactic head frame, usually under local anesthesia, followed by neuroradiologic imaging, most frequently MRI. Other imaging procedures performed in conjunction with stereotactic radiosurgery have included angiography and CT. After precise stereotactic localization of the target, the radiosurgical procedure commences. Most cooperative patients require only mild sedation/analgesia for the procedure. Uncooperative adults, those with movement disorders, and pediatrics patients may require general anesthesia for any or all components of the procedure. The total duration of the anesthetic may be several hours.[202] [203] [208] Attention to fluid status, temperature maintenance, and pressure point padding is particularly important during these potentially long procedures. If general anesthesia is required, intravenous anesthesia with propofol may provide advantages in maintenance during the multiple patient transfers entailed by the procedure.[202] Mechanisms to maintain consistent standard monitoring throughout the procedure and transfers need to be in place. After the procedure, the patient goes to a fully staffed and equipped recovery area and is discharged after meeting standard discharge criteria.

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