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Misdirected laser energy may perforate a viscus[31] [32] [33] [34] or a large blood vessel (vessels >5 mm are not coagulable by laser). Laser-induced pneumothorax has been reported after a laryngeal procedure.[35] With an Nd:YAG system, the depth of damage is impossible to assess accurately or immediately, and perforation and bleeding may not occur until edema and necrosis have become maximal several days postoperatively.
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