REFERENCES
1.
Shackelford DP, Lalikos JF: Estrogen replacement
therapy and the surgeon. Am J Surg 179:333–336, 2000.
2.
Bailes B: Perioperative care of the elderly surgical
patient. AORN J 72:186–207, 2000.
3.
Rigberg D, Cole M, Hiyama D, McFadden D: Surgery
in the nineties. Am Surg 66:813–816, 2000.
4.
Small S: Age-related memory decline: Current concepts
and future directions. Arch Neurol 58:360–364, 2001.
5.
Ge Y, Grossman RJ, Babb JS, et al: Age-related
total gray matter and white matter changes in normal adult brain. Part I: Volumetric
MR imaging analysis. AJNR Am J Neuroradiol 23:1327–1333, 2002.
6.
Peters A: Structural changes that occur during
normal aging of primate cerebral hemispheres. Neurosci Biobehav Rev 26:733–741,
2002.
7.
Priebe H: The aged cardiovascular risk patient.
Br J Anaesth 85:763–778, 2000.
8.
O'Rourke M: Function of conduit arteries. In
O'Rourke MF, Safar M, Dzau VJ (eds): Arterial Vasodilation; Mechanisms and Therapy.
Philadelphia, Lea & Febiger, 1993, pp 1–9.
9.
Nichols WM, O'Rourke MF, Avolio AP, et al: Age-related
changes in left ventricular/arterial coupling, ventricular/vascular coupling. In
Yin F (ed): Clinical, Physiologic, and Engineering Aspects. New York, Springer-Verlag,
1987, pp 79–115.
10.
O'Rourke MF, Kelly R, Avolio AP: Factors determining
normal pressure pulse contour. In O'Rourke MF, Kelly
R, Avolio AP (eds): The Arterial Pulse. Philadelphia, Lea & Febiger, 1992,
pp 47–72.
11.
Rooke G: Autonomic and cardiovascular function
in the geriatric patient. Anesthesiol Clin North Am 18:31–46, 2000.
12.
Tresch D: Clinical manifestations, diagnostic
assessment, and etiology of heart failure in elderly patients. Clin Geriatr Med
16:445–456, 2000.
13.
Otto CM, Lind BK, Kitzman DW, et al: Association
of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly.
N Engl J Med 341:142–147, 1999.
14.
Boon A, Cheriex E, Lodder J, Kessels F: Cardiac
valve calcification: Characteristics of patients with calcification of the mitral
annulus or aortic valve. Heart 78:472–474, 1997.
15.
Zaugg M, Lucchinetti E: Respiratory function in
the elderly. Anesthesiol Clin North Am 18:47–58, 2000.
16.
Fredman B, Lahav M, Zohar E, et al: The effect
of midazolam premedication on mental and psychomotor recovery in geriatric patients
undergoing brief surgical procedures. Anesth Analg 89:1161–1166, 1999.
17.
Nunn J: Nunn's Applied Respiratory Physiology.
Oxford, Butterworth-Heinemann, 1993.
18.
Dib JC, Abergel E, Rovani C, et al: The age of
the patient should be taken into account when interpreting Doppler assessed pulmonary
artery pressures. J Am Soc Echocardiogr 10:72–73, 1997.
19.
Epstein M: Aging and the kidney. J Am Soc Nephrol
7:1106–1122, 1996.
20.
Shafer S: The pharmacology of anesthetic drugs
in elderly patients. Anesthesiol Clin North Am 18:1–29, 2000.
21.
Eger E: Age, minimum alveolar anesthetic concentration,
and minimum alveolar anesthetic concentration-awake. Anesth Analg 93:947–953,
2001.
22.
Homer TD, Stanski DR: The effect of increasing
age on thiopental disposition and anesthetic requirement. Anesthesiology 62:714–724,
1985.
23.
Arden JR, Holley FO, Stanski DR: Increased sensitivity
to etomidate in the elderly: Initial distribution versus altered brain response.
Anesthesiology 65:19–27, 1986.
24.
Schnider TW, Minto CF, Shafer SL, et al: The influence
of age on propofol pharmacodynamics. Anesthesiology 90:1502–1516, 1999.
25.
Bell GD, Spickett GP, Reeve PA, et al: Intravenous
midazolam for upper gastrointestinal endoscopy: A study of 800 consecutive cases
relating dose to age and sex of patient. Br J Clin Pharmacol 23:241–243, 1987.
26.
Maitre PO, Buhrer M, Thomson D, Stanski DR: A
three-step approach combining Bayesian regression and NONMEM population analysis:
Application to midazolam. J Pharmacokinet Biopharm 19:377–384, 1991.
27.
Macintyre PE, Jarvis DA: Age is the best predictor
of postoperative morphine requirements. Pain 64:357–364, 1996.
28.
Baillie SP, Bateman DN, Coates PE, Woodhouse KW:
Age and the pharmacokinetics of morphine. Age Ageing 18:258–262, 1989.
29.
Wolff J, Bisler D, Christensen CB, et al: Influence
of renal function on the elimination of morphine and morphine glucuronides. Eur
J Clin Pharmacol 34:353–357, 1988.
30.
Sear JW, Hand CW, Moore RA: Studies on morphine
disposition: Plasma concentrations of morphine and its metabolites in anesthetized
middle-aged and elderly surgical patients. J Clin Anesth 1:164–169, 1989.
31.
Minto CF, Schnider TW, Shafer SL: Pharmacokinetics
and pharmacodynamics of remifentanil. II. Model application. Anesthesiology 86:24–33,
1997.
32.
Minto CF, Schnider TW, Egan TD, et al: Influence
of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil.
I. Model development. Anesthesiology 86:10–23, 1997.
33.
McLeod K, Hull CJ, Watson MJ: Effects of ageing
on the pharmacokinetics of pancuronium. Br J Anaesth 51:435–438, 1979.
34.
Rupp SM, Castagnoli KP, Fisher DM, Miller RD:
Pancuronium and vecuronium pharmacokinetics and pharmacodynamics in younger and elderly
adults. Anesthesiology 67:45–49, 1987.
35.
Kent AP, Parker CJ, Hunter JM: Pharmacokinetics
of atracurium and laudanosine in the elderly. Br J Anaesth 63:661–666, 1989.
36.
Lien CA, Matteo RS, Ornstein E, et al: Distribution,
elimination, and action of vecuronium in the elderly. Anesth Analg 73:39–42,
1991.
37.
Veering BT, Burm AG, Spierdijk J: Spinal anaesthesia
with hyperbaric bupivacaine. Effects of age on neural blockade and pharmacokinetics.
Br J Anaesth 60:187–194, 1988.
38.
Veering BT, Burm AG, van Kleef JW, et al: Spinal
anesthesia with glucose-free bupivacaine: Effects of age on neural blockade and
pharmacokinetics. Anesth Analg 66:965–970, 1987.
39.
Veering BT, Burm AG, van Kleef JW, et al: Epidural
anesthesia with bupivacaine: Effects of age on neural blockade and pharmacokinetics.
Anesth Analg 66:589–593, 1987.
40.
Paqueron X, Boccara G, Bendahou M, et al: Brachial
plexus nerve block exhibits prolonged duration in the elderly. Anesthesiology 97:1245–1249,
2002.
41.
Palmer R: Geriatric assessment. Med Clin North
Am 83:1503–1523, 1999.
42.
Chung OY, Beattie C, Friesinger GC: Assessment
of cardiovascular risks and overall risks for noncardiac surgery. Cardiol Clin 17:197–211,
1999.
43.
Magaziner J, Simonsick EM, Kashner TM, et al:
Predictors of functional recovery one year following hospital discharge for hip fracture:
A prospective study. J Gerontol 45:M101–M107, 1990.
44.
Eisler J, Cornwall R, Strauss E, et al: Outcomes
of elderly patients with nondisplaced femoral neck fractures. Clin Orthop 399:52–58,
2002.
45.
Inouye SK, Peduzzi PN, Robison JT, et al: Importance
of functional measures in predicting mortality among older hospitalized patients.
JAMA 279:1187–1193, 1998.
46.
Holt EM, Evans RA, Hindley CJ, Metcalfe JW: 1000
femoral neck fractures: The effect of pre-injury mobility and surgical experience
on outcome. Injury 25:91–95, 1994.
47.
Eagle KA, Brundage BH, Chaitman BR, et al: Guidelines
for perioperative cardiovascular evaluation for noncardiac surgery: An abridged
version of the report of the American College of Cardiology/American Heart Association
Task Force on Practice Guidelines. Mayo Clin Proc 72:524–531, 1997.
48.
Ware JE Jr, Sherbourne CD: The MOS 36-item short-form
health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473–483,
1992.
49.
Mangione CM, Goldman L, Orav EJ, et al: Health-related
quality of life after elective surgery: Measurement of longitudinal changes. J
Gen Intern Med 12:686–697, 1997.
50.
Katz PR, Grossberg GT, Potter JF, Solomon DH:
Geriatrics Syllabus for Specialists. New York, American Geriatrics Society, 2002.
51.
Crouch DS, McLafferty RB, Karch LA, et al: A prospective
study of discharge disposition after vascular surgery. J Vasc Surg 34:62–68,
2001.
52.
Tiret L, Desmonts JM, Hatton F, Vourc'h G: Complications
associated with anaesthesia—a prospective survey in France. Can Anaesth Soc
J 33:336–344, 1986.
53.
Jin F, Chung F: Minimizing perioperative adverse
events in the elderly. Br J Anaesth 877:608–624, 2001.
54.
Finlayson EV, Birkmeyer JD: Operative mortality
with elective surgery in older adults. Eff Clin Pract 4:172–177, 2001.
55.
Pedersen T, Eliasen K, Henriksen E: A prospective
study of mortality associated with anaesthesia and surgery: Risk indicators of mortality
in hospital. Acta Anaesthesiol Scand 34:176–182, 1990.
56.
Forrest JB, Rehder K, Cahalan MK, Goldsmith CH:
Multicenter study of general anesthesia. III. Predictors of severe perioperative
adverse outcomes. Anesthesiology 76:3–15, 1992.
57.
Bellomo R, Goldsmith D, Russell S, Uchino S: Postoperative
serious adverse events in a teaching hospital: A prospective study. Med J Aust
176:216–218, 2002.
58.
Ackermann RJ, Vogel RL, Johnson LA, et al: Surgery
in nonagenarians: Morbidity, mortality, and functional outcome. J Fam Pract 40:129–135,
1995.
59.
Shah MR, Aharonoff GB, Wolinsky P, et al: Outcome
after hip fracture in individuals ninety years of age and older. J Orthop Trauma
15:34–39, 2001.
60.
Edwards AE, Seymore DG, McCarthy JM, Crumplin MK:
A 5-year survival study of general surgical patients aged 65 years and over. Anaesthesia
51:3–10, 1996.
61.
Hosking MP, Warner MA, Lobdell CM, et al: Outcomes
of surgery in patients 90 years of age and older. JAMA 261:1909–1915, 1989.
62.
Warner MA, Saletel RA, Schroeder DR, et al: Outcomes
of anesthesia and surgery in people 100 years of age and older. J Am Geriatr Soc
46:988–993, 1998.
63.
Kazmers A, Perkins AJ, Huber TS, Jacobs LA: Carotid
surgery in octogenarians in Veterans Affairs medical centers. J Surg Res 81:87–90,
1999.
64.
Leung JM, Dzankic S: Relative importance of preoperative
health status versus intraoperative factors in predicting postoperative adverse outcomes
in geriatric surgical patients. J Am Geriatr Soc 49:1080–1085, 2001.
65.
Finucane TE, Harper M: Ethical decision-making
near the end of life. Clin Geriatr Med 12:369–377, 1996.
66.
Appelbaum PS, Grisso T: Assessing patients' capacities
to consent to treatment. N Engl J Med 319:1635–1638, 1988.
67.
Ouslander JG, Tymchuk AJ, Rahbar B: Health care
decisions among elderly long-term care residents and their potential proxies. Arch
Intern Med 149:1367–1372, 1989.
68.
Cohen CB, Cohen PJ: Do-not-resuscitate orders
in the operating room. N Engl J Med 325:1879–1882, 1991.
69.
Fletcher K, Forch W: Acute symptom assessment:
Determining the seriousness of the presentation. Lippincotts Prim Care Pract 3:216–328,
1999.
70.
Feldman C: Pneumonia in the elderly. Clin Chest
Med 20:563–573, 1999.
71.
Hecht A, Sipple J, Deitz S, Williams P: Diagnosis
and treatment of pneumonia in the nursing home. Nurse Pract 20:24, 27–28,
35–39, 1995.
72.
Johnson JC, Jayadevappa R, Baccash PD, Taylor L:
Nonspecific presentation of pneumonia in hospitalized older people: Age effect
or dementia? J Am Geriatr Soc 48:1316–1320, 2000.
73.
Heruti RJ, Lusky A, Barell V, et al: Cognitive
status at admission: Does it affect the rehabilitation outcome of elderly patients
with hip fracture? Arch Phys Med Rehabil 80:432–436, 1999.
74.
Bernstein GM, Offenbartl SK: Adverse surgical
outcomes among patients with cognitive impairments. Am Surg 57:682–690, 1991.
75.
Ritchie K, Polge C, de Roquefeuil G, et al: Impact
of anesthesia on the cognitive functioning of the elderly. Int Psychogeriatr 9:309–326,
1997.
76.
Dijkstra JB, Van Boxtel MP, Houx PJ, Jolles J:
An operation under general anesthesia as a risk factor for age-related cognitive
decline: Results from a large cross-sectional population study. J Am Geriatr Soc
46:1258–1265, 1998.
77.
Dyer CB, Ashton CM, Teasdale TA: Postoperative
delirium. A review of 80 primary data-collection studies. Arch Intern Med 155:461–465,
1995.
78.
Folstein MF, Folstein SE, McHugh PR: "Mini-mental
state." A practical method for grading the cognitive state of patients for the clinician.
J Psychiatr Res 12:189–198, 1975.
79.
Newman MF, Kirchner JL, Phillips-Bute B, et al:
Longitudinal assessment of neurocognitive function after coronary-artery bypass
surgery. N Engl J Med 344:395–402, 2001.
80.
Newman MF, Grocott HP, Mathew JP, et al: Report
of the substudy assessing the impact of neurocognitive function on quality of life
5 years after cardiac surgery. Stroke 32:2874–2881, 2001.
81.
Dijkstra JB, Houx JJ, Jolles J: Cognition after
major surgery in the elderly: Test performance and complaints. Br J Anaesth 82:867–874,
1999.
82.
Moller JT, Cluitmans P, Rasmussen LS, et al: Long-term
postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators.
International Study of Post-Operative Cognitive Dysfunction. Lancet 351:857–861,
1998.
83.
Abildstrom H, Rasmussen LS, Rentowl P, et al:
Cognitive dysfunction 1–2 years after non-cardiac surgery in the elderly.
ISPOCD group. International Study of Post-Operative Cognitive Dysfunction. Acta
Anaesthesiol Scand 44:1246–1251, 2000.
84.
Ancelin ML, de Roquefeuil G, Ledesert B, et al:
Exposure to anaesthetic agents, cognitive functioning and depressive symptomatology
in the elderly. Br J Psychiatry 178:360–366, 2001.
85.
Goldstein MZ, Young BL, Fogel BS, Benedict RH:
Occurrence and predictors of short-term mental and functional changes in older adults
undergoing elective surgery under general anesthesia. Am J Geriatr Psychiatry 6:42–52,
1998.
86.
Cryns AG, Gorey KM, Goldstein MZ: Effects of surgery
on the mental status of older persons. A meta-analytic review. J Geriatr Psychiatry
Neurol 3:184–191, 1990.
87.
Goldstein MZ, Fogel BS, Young BL: Effect of elective
surgery under general anesthesia on mental status variables in elderly women and
men: 10-month follow-up. Int Psychogeriatr 8:135–149, 1996.
88.
Marcantonio ER, Goldman L, Mangione CM, et al:
A clinical prediction rule for delirium after elective noncardiac surgery. JAMA
271:134–139, 1994.
89.
Gallinat J, Moller H, Moser RL, Hegerl U: Postoperative
delirium: Risk factors, prophylaxis and treatment [in German]. Anaesthesist 48:507–518,
1999.
90.
Parikh SS, Chung F: Postoperative delirium in
the elderly. Anesth Analg 80:1223–1232, 1995.
91.
Magaziner J, Simonsick EM, Kashner TM, et al:
Survival experience of aged hip fracture patients. Am J Public Health 79:274–278,
1989.
92.
Marcantonio ER, Flacker JM, Michaels M, Resnick
NM: Delirium is independently associated with poor functional recovery after hip
fracture. J Am Geriatr Soc 48:618–624, 2000.
93.
Dolan MM, Hawkes WG, Zimmerman SI, et al: Delirium
on hospital admission in aged hip fracture patients: Prediction of mortality and
2-year functional outcomes. J Gerontol A Biol Sci Med Sci 55:M527–M534, 2000.
94.
Diagnostic and Statistical Manual of Mental Disorders,
4th ed. Washington, DC, American Psychiatric Association, 1994, pp 129–133.
95.
Inouye SK, van Dyck CH, Alessi CA, et al: Clarifying
confusion: The confusion assessment method. A new method for detection of delirium.
Ann Intern Med 113:941–948, 1990.
96.
Marcantonio E, Ta T, Duthie E, Resnick NM: Delirium
severity and psychomotor types: Their relationship with outcomes after hip fracture
repair. J Am Geriatr Soc 50:850–857, 2002.
97.
Pompei P, Foreman M, Rudberg MA, et al: Delirium
in hospitalized older persons: Outcomes and predictors. J Am Geriatr Soc 42:809–815,
1994.
98.
Inouye SK, Viscoli CM, Horwitz RI, et al: A predictive
model for delirium in hospitalized elderly medical patients based on admission characteristics.
Ann Intern Med 119:474–481, 1993.
99.
Inouye SK, Charpentier PA: Precipitating factors
for delirium in hospitalized elderly persons. Predictive model and interrelationship
with baseline vulnerability. JAMA 275:852–857, 1996.
100.
Edlund A, Lundstrom M, Lundstrom G, et al: Clinical
profile of delirium in patients treated for femoral neck fractures. Dement Geriatr
Cogn Disord 10:325–329, 1999.
101.
Flacker JM, Lipsitz LA: Neural mechanisms of
delirium: Current hypotheses and evolving concepts. J Gerontol A Biol Sci Med Sci
54:B239–B246, 1999.
102.
van der Mast RC: Pathophysiology of delirium.
J Geriatr Psychiatry Neurol 11:138–145, 1998.
103.
Herrmann M, Ebert AD, Galazky I, et al: Neurobehavioral
outcome prediction after cardiac surgery: Role of neurobiochemical markers of damage
to neuronal and glial brain tissue. Stroke 31:645–650, 2000.
104.
Rasmussen LS, Christiansen M, Rasmussen H, et
al: Do blood concentrations of neurone specific enolase and S-100 beta protein reflect
cognitive dysfunction after abdominal surgery? ISPOCD Group. Br J Anaesth 84:242–244,
2000.
105.
Edmonds CR, Barbut D, Hager D, Sharrock NE: Intraoperative
cerebral arterial embolization during total hip arthroplasty. Anesthesiology 93:315–318,
2000.
106.
Elie M, Cole MG, Primeau FJ, Bellavance F: Delirium
risk factors in elderly hospitalized patients. J Gen Intern Med 13:204–212,
1998.
107.
van der Mast RC, van den Broek WW, Fekkes D, et
al: Incidence of and preoperative predictors for delirium after cardiac surgery.
J Psychosom Res 46:479–483, 1999.
108.
van der Mast RC, van den Broek WW, Fekkes D, et
al: Is delirium after cardiac surgery related to plasma amino acids and physical
condition? J Neuropsychiatry Clin Neurosci 12:57–63, 2000.
109.
Nierman E, Zakrzewski K: Recognition and management
of preoperative risk. Rheum Dis Clin North Am 25:585–622, 1999.
110.
Kaneko T, Takahashi S, Naka T, et al: Postoperative
delirium following gastrointestinal surgery in elderly patients. Surg Today 27:107–111,
1997.
111.
Marcantonio ER, Goldman L, Orav EJ, et al: The
association of intraoperative factors with the development of postoperative delirium.
Am J Med 105:380–384, 1998.
112.
Aakerlund LP, Rosenberg J: Postoperative delirium:
Treatment with supplementary oxygen. Br J Anaesth 72:286–290, 1994.
113.
Clayer M, Bruckner J: Occult hypoxia after femoral
neck fracture and elective hip surgery. Clin Orthop 370:265–271, 2000.
114.
Lynch EP, Lazor MA, Gellis JE, et al: The impact
of postoperative pain on the development of postoperative delirium. Anesth Analg
86:781–785, 1998.
115.
Inouye SK, Bogardus ST Jr, Charpentier PA, et
al: A multicomponent intervention to prevent delirium in hospitalized older patients.
N Engl J Med 340:669–676, 1999.
116.
Maaravi Y, Ginsberg G, Cohen A, Stessman J, Berry
EM: The nutritional status of 70 year olds in Jerusalem. Isr J Med Sci 32:620–625,
1996.
117.
Azad N, Murphy J, Amos SS, Toppan J: Nutrition
survey in an elderly population following admission to a tertiary care hospital.
CMAJ 161:511–515, 1999.
118.
Potter J, Klipstein K, Reilly JJ, Roberts M:
The nutritional status and clinical course of acute admissions to a geriatric unit.
Age Ageing 24:131–136, 1995.
119.
Gibbs J, Cull W, Henderson W, et al: Preoperative
serum albumin level as a predictor of operative mortality and morbidity: Results
from the National VA Surgical Risk Study. Arch Surg 134:36–42, 1999.
120.
Koval KJ, Maurer SG, Su ET, et al: The effects
of nutritional status on outcome after hip fracture. J Orthop Trauma 13:164–169,
1999.
121.
Holmes J, House A: Psychiatric illness predicts
poor outcome after surgery for hip fracture: A prospective cohort study. Psychol
Med 30:921–929, 2000.
122.
Berggren D, Gustafson Y, Eriksson B, et al: Postoperative
confusion after anesthesia in elderly patients with femoral neck fractures. Anesth
Analg 66:497–504, 1987.
123.
Heijmeriks JA, Pourrier S, Dassen P, et al: Comparison
of quality of life after coronary and/or valvular cardiac surgery in patients >
or =75 years of age with younger patients. Am J Cardiol 83:1129–1132, 1999.
124.
Kudoh A, Katagai H, Takazawa T: Antidepressant
treatment for chronic depressed patients should not be discontinued prior to anesthesia.
Can J Anaesth 49:132–136, 2002.
125.
Perhonen MA, Zuckerman JH, Levine BD: Deterioration
of left ventricular chamber performance after bed rest: "Cardiovascular deconditioning"
or hypovolemia? Circulation 103:1851–1857, 2001.
126.
Bloomfield S: Changes in musculoskeletal structure
and function with prolonged bed rest. Med Sci Sports Exerc 29:197–206, 1997.
127.
Warren JL, Bacon WE, Harris T, et al: The burden
and outcomes associated with dehydration among US elderly, 1991. Am J Public Health
84:1265–1269, 1994.
128.
Johnson I: Alcohol problems in old age: A review
of recent epidemiological research. Int J Geriatr Psychiatry 15:575–581, 2000.
129.
Mulinga J: Elderly people with alcohol-related
problems: Where do they go? Int J Geriatr Psychiatry 14:564–566, 1999.
130.
Arozullah AM, Khuri SF, Henderson WG, et al:
Development and validation of a multifactorial risk index for predicting postoperative
pneumonia after major noncardiac surgery. Ann Intern Med 135:847–857, 2001.
131.
Sengstaken EA, King SA: The problems of pain
and its detection among geriatric nursing home residents. J Am Geriatr Soc 41:541–544,
1993.
132.
Gallagher RM, Verma S, Mossey J: Chronic pain.
Sources of late-life pain and risk factors for disability. Geriatrics 55:40–44,
2000.
133.
Cramer GW, Galer BS, Mendelson MA, Thompson GD:
A drug use evaluation of selected opioid and nonopioid analgesics in the nursing
facility setting. J Am Geriatr Soc 48:398–404, 2000.
134.
Schein OD, Katz J, Bass EB, et al: The value
of routine preoperative medical testing before cataract surgery. Study of Medical
Testing for Cataract Surgery. N Engl J Med 342:168–175, 2000.
135.
Sanders DP, McKinney FW, Harris WH: Clinical
evaluation and cost effectiveness of preoperative laboratory assessment on patients
undergoing total hip arthroplasty. Orthopedics 12:1449–1453, 1989.
136.
Dzankic S, Pastor D, Gonzalez C, Leung JM: The
prevalence and predictive value of abnormal preoperative laboratory tests in elderly
surgical patients. Anesth Analg 932:301–308, 2001.
137.
Roy R: Choosing general versus regional anesthesia
for the elderly. Anesthesiol Clin North Am 18:91–104, 2000.
138.
Norris EJ, Beattie C, Perler BA, et al: Double-masked
randomized trial comparing alternate combinations of intraoperative anesthesia and
postoperative analgesia in abdominal aortic surgery. Anesthesiology 95:1054–1067,
2001.
139.
O'Hara DA, Duff A, Berlin JA, et al: The effect
of anesthetic technique on postoperative outcomes in hip fracture repair. Anesthesiology
92:947–957, 2000.
140.
Valentin N, Lomholt B, Jensen JS, et al: Spinal
or general anaesthesia for surgery of the fractured hip? A prospective study of
mortality in 578 patients. Br J Anaesth 58:284–291, 1986.
141.
Davis FM, Woolner DF, Frampton C, et al: Prospective,
multi-centre trial of mortality following general or spinal anaesthesia for hip fracture
surgery in the elderly. Br J Anaesth 59:1080–1088, 1987.
142.
Koval KJ, Aharonoff GB, Rosenberg AD, et al:
Functional outcome after hip fracture. Effect of general versus regional anesthesia.
Clin Orthop 348:37–41, 1998.
143.
Rosenfeld BA, Beattie C, Christopherson R, et
al: The effects of different anesthetic regimens on fibrinolysis and the development
of postoperative arterial thrombosis. Perioperative Ischemia Randomized Anesthesia
Trial Study Group. Anesthesiology 79:435–443, 1993.
144.
Prevention of pulmonary embolism and deep vein
thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet
355:1295–1302, 2000.
145.
Covert CR, Fox GS: Anaesthesia for hip surgery
in the elderly. Can J Anaesth 36:311–319, 1989.
146.
Williams-Russo P, Sharrock NE, Haas SB, et al:
Randomized trial of epidural versus general anesthesia: Outcomes after primary
total knee replacement. Clin Orthop 331:199–208, 1996.
147.
Christopherson R, Beattie C, Frank SM, et al:
Perioperative morbidity in patients randomized to epidural or general anesthesia
for lower extremity vascular surgery. Perioperative Ischemia Randomized Anesthesia
Trial Study Group. Anesthesiology 79:422–434, 1993.
148.
Modig J: Beneficial effects on intraoperative
and postoperative blood loss in total hip replacement when performed under lumbar
epidural anesthesia. An explanatory study. Acta Chir Scand Suppl 550:95–100,
1989.
149.
Shir Y, Raja SN, Frank SM, Brendler CB: Intraoperative
blood loss during radical retropubic prostatectomy: Epidural versus general anesthesia.
Urology 45:993–999, 1995.
150.
Moller JT, Wittrup M, Johansen SH: Hypoxemia
in the postanesthesia care unit: An observer study. Anesthesiology 73:890–895,
1990.
151.
Frank SM, Beattie C, Christopherson R, et al:
Unintentional hypothermia is associated with postoperative myocardial ischemia.
The Perioperative Ischemia Randomized Anesthesia Trial Study Group. Anesthesiology
78:468–476, 1993.
152.
Frank SM, Fleisher LA, Breslow MJ, et al: Perioperative
maintenance of normothermia reduces the incidence of morbid cardiac events. A randomized
clinical trial. JAMA 277:1127–1134, 1997.
153.
Frank SM, El-Rahmany HK, Cattaneo CG, Barnes RA:
Predictors of hypothermia during spinal anesthesia. Anesthesiology 92:1330–1334,
2000.
154.
Liu LL, Leung JM: Predicting adverse postoperative
outcomes in patients aged 80 years or older. J Am Geriatr Soc 48:405–412,
2000.
155.
Shafer S: The role of newer opioids in geriatric
anesthesia. Acta Anaesthesiol Belg 49:91–103, 1998.
156.
Berg H, Roed J, Viby-Mogensen J, et al: Residual
neuromuscular block is a risk factor for postoperative pulmonary complications.
A prospective, randomised, and blinded study of postoperative pulmonary complications
after atracurium, vecuronium and pancuronium. Acta Anaesthesiol Scand 41:1095–1103,
1997.
157.
Chen X, Zhao M, White PF, et al: The recovery
of cognitive function after general anesthesia in elderly patients: A comparison
of desflurane and sevoflurane. Anesth Analg 93:1489–1494, 2001.
158.
Slogoff S, Reul GJ, Keats AS, et al: Role of
perfusion pressure and flow in major organ dysfunction after cardiopulmonary bypass.
Ann Thorac Surg 50:911–918, 1990.
159.
Gold JP, Charlson ME, Williams-Russo P, et al:
Improvement of outcomes after coronary artery bypass. A randomized trial comparing
intraoperative high versus low mean arterial pressure. J Thorac Cardiovasc Surg
110:1302–1311, discussion 1311–1314, 1995.
160.
Williams-Russo P, Sharrock NE, Mattis S, et al:
Randomized trial of hypotensive epidural anesthesia in older adults. Anesthesiology
91:926–935, 1999.
161.
Sandham JD, Hull RD, Brant RF, et al: A randomized,
controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients.
N Engl J Med 348:5–14, 2003.
162.
Seymour DG, Vaz FG: A prospective study of elderly
general surgical patients: II. Post-operative complications. Age Ageing 18:316–326,
1989.
163.
Vodinh J, Bonnet F, Touboul C, et al: Risk factors
of postoperative pulmonary complications after vascular surgery. Surgery 105:360–365,
1989.
164.
Mitchell CK, Smoger SH, Pfeifer MP, et al: Multivariate
analysis of factors associated with postoperative pulmonary complications following
general elective surgery. Arch Surg 133:194–198, 1998.
165.
Wong DH, Weber EC, Schell MJ, et al: Factors
associated with postoperative pulmonary complications in patients with severe chronic
obstructive pulmonary disease. Anesth Analg 80:276–284, 1995.
166.
Aviv J: Effects of aging on sensitivity of the
pharyngeal and supraglottic areas. Am J Med 103(Suppl 5A):74S–76S, 1997.
167.
Hogue CW Jr, Lappas GD, Creswell LL, et al: Swallowing
dysfunction after cardiac operations. Associated adverse outcomes and risk factors
including intraoperative transesophageal echocardiography. J Thorac Cardiovasc Surg
110:517–522, 1995.
168.
Gray SL, Slager M, Lestico MR, Jalaluddin M:
Adverse drug events in hospitalized elderly. J Gerontol A Biol Sci Med Sci 53:M59–M63,
1998.
169.
Tucker MA, Andrew MF, Ogle SJ, Davison JG: Age-associated
change in pain threshold measured by transcutaneous neuronal electrical stimulation.
Age Ageing 18:241–246, 1989.
170.
Washington LL, Gibson SJ, Helme RD: Age-related
differences in the endogenous analgesic response to repeated cold water immersion
in human volunteers. Pain 89:89–96, 2000.
171.
Gibson SJ, Helme RD: Age-related differences
in pain perception and report. Clin Geriatr Med 17:433–456, 2001.
172.
Cohen-Mansfield J, Lipson S: Pain in cognitively
impaired nursing home residents: How well are physicians diagnosing it? J Am Geriatr
Soc 50:1039–1044, 2002.
173.
Egbert A: Postoperative pain management in the
frail elderly. Clin Geriatr Med 12:583–599, 1996.
174.
Tovar E: One-day admission for major lung resections
in septuagenarians and octogenarians: A comparative study with a younger cohort.
Eur J Cardiothorac Surg 20:449–453, 2001.
175.
Lee JH, Swain B, Andrey J, et al: Fast track
recovery of elderly coronary bypass surgery patients. Ann Thorac Surg 68:437–441,
1999.
176.
Chuter TA, Gordon RL, Reilly LM, et al: Abdominal
aortic aneurysm in high-risk patients: Short- to intermediate-term results of endovascular
repair. Radiology 210:361–365, 1999.
177.
Efron DT, Bender JS: Laparoscopic surgery in
older adults. J Am Geriatr Soc 49:658–663, 2001.
178.
Chung F, Merzei G, Tong D: Adverse events in
ambulatory surgery. A comparison between elderly and younger patients. Can J Anaesth
46:309–321, 1999.
