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PREPARATION FOR THE PROCEDURE

Initial Evaluation

Someone other than the obstetrician should evaluate and resuscitate the neonate. If intrauterine asphyxia is known to exist or is strongly suspected ( Table 59-2 ), at least two additional people are required to resuscitate the neonate: one to ventilate the lungs and the other to insert an umbilical artery or venous catheter, or both, and correct acid-base and blood volume abnormalities. A plan for the resuscitation of each neonate should be developed and understood by everyone in the delivery room before the neonate's birth. There should be at least one person immediately available who is skilled in neonatal resuscitation. A second person should be designated as backup and should be available in a reasonable amount of time to assist in the resuscitation.

After breathing is established and the umbilical cord has stopped pulsating, the cord is cut and the neonate is taken to the resuscitation table. Holding the neonate below the introitus of the mother increases blood volume and causes polycythemia.[57] Raising the neonate above the level of the introitus or clamping the umbilical cord early decreases blood volume. [58]

Stripping blood from the umbilical cord to the neonate increases blood volume,[59] respiratory rate,[60] lung water,[61] pulmonary artery pressure, and PaCO2 . [62] Lung compliance, FRC, and PaO2 [63] decrease. Figure 59-6 shows the effects of early and late cord clamping on placental blood volume. The larger the placental blood volume, the smaller is the neonate's blood volume. Early cord clamping can deprive neonates of up to 30 mL of blood per 1 kg of body weight.[58]

If the neonate is flaccid, pale, limp, or cyanotic, the umbilical cord should be clamped and cut and the neonate handed off to be resuscitated. However, when this is done, there is a high likelihood that the neonate will be hypovolemic because the umbilical cord was clamped early.

The neonate should be placed in a radiantly heated resuscitation bed with the head slightly lower than the body, and the airway should be cleared of secretions and blood by gently suctioning the mouth and nose with a bulb syringe. Prolonged suctioning can cause vomiting and arrhythmias, the most common of which is bradycardia, but ventricular arrhythmias occur in 10% to 20% of neonates who are suctioned vigorously while hypoxic.

If the respiratory pattern and color are normal, nothing more is required except to dry the neonate with a towel and quickly insert a suction catheter into the posterior pharynx through each nostril to rule out choanal atresia. The same catheter is then passed through the mouth into the stomach to rule out esophageal atresia and small bowel atresia and to empty the stomach of its contents.


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TABLE 59-2 -- Disorders frequently associated with asphyxia at birth
Maternal Conditions
Elderly primigravida (>35 years of age)
Diabetes
Hypertension
Toxemia
Maternal treatment with any of the following
  Glucocorticoids
  Diuretics
  Antimetabolites
  Reserpine, lithium
  Magnesium
  Ethyl alcohol
  β-Adrenergic drugs (to stop premature labor)
Abnormal estriol levels
Anemia (hemoglobin level less than 10 g/100 mL)
Blood type or group isoimmunization
Previous birth of child with a hereditary disease
Current maternal infection or infection during pregnancy with rubella, herpes simplex, or syphilis
Abruptio placentae
Placenta previa
Antepartum hemorrhage
History of previous infant with jaundice, thrombocytopenia, cardiorespiratory distress, or congenital anomalies
Narcotic, barbiturate, tranquilizer, or psychedelic drugs
Ethyl alcohol intoxication
History of previous neonatal death
Prolonged rupture of membranes
Conditions of Labor and Delivery
Forceps delivery other than low elective
Vacuum extraction delivery
Breech presentation and delivery or other abnormal presentation
Cesarean section
Prolonged labor
Prolapsed umbilical cord
Cephalopelvic disproportion
Maternal hypotension
Sedative or analgesic drugs given intravenously within 1 hour of delivery or intramuscularly within 2 hours of delivery
Fetal Conditions
Multiple births
Polyhydramnios
Meconium-stained amniotic fluid
Abnormal heart rate or rhythm
Acidosis (fetal scalp capillary blood)
Decreased rate of growth (uterine size)
Premature delivery
Amniotic fluid surfactant test negative or intermediate within 24 hours of delivery
Neonatal Conditions
Birth asphyxia
Birth weight (inappropriate for gestational age)
Meconium staining of the skin, nails, or umbilical cord
Signs of cardiorespiratory distress


Figure 59-6 The effects of early and late cord clamping on placental blood volume. (Adapted from Ogata ES, Kitterman JA, Phibbs RH, et al: The effect of time of cord clamping and maternal blood pressure on placental transfusion with cesarean section. Am J Obstet Gynecol 128:197, 1977.)

Bilateral choanal atresia may be lethal because the airway becomes completely obstructed when he or she closes the mouth. When the mouth is open, the neonate is pink; when the mouth is closed, the neonate continues to make breathing efforts, but no gas movement into or out of the lung can take place. To alleviate the airway obstruction, the physician inserts an oral airway or an endotracheal tube to prevent the tongue from making a tight seal with the pharyngeal wall. If the diagnosis of choanal atresia is made, the neonate should be seen by a nose and throat surgeon who specializes in pediatric surgery, and the obstruction should be relieved surgically.

The 1-minute Apgar score can be used to guide resuscitation, but it is only a guide. The physician should not wait until 1 minute has passed before initiating resuscitation. The primary purpose of Apgar scoring is to ensure that each neonate is closely evaluated during the first few minutes of life.

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